CELL LINES

Contributor Information
- Name Eric Kenneth Parkinson
- Institute Cancer Research UK, Glasgow: The Beatson Institute
Tool Details
- Tool name: BICR 3 Cell Line
- Tool type: Cell Lines
- Organism: Human
- Tissue: Alveolus
- Cancer type: Lung cancer
- Disease: Cancer
- Growth properties: Adherent
- Model: Tumour line
- Conditional: Yes
- Description: Adherent keratinocyte cell line derived from a squamous cell carcinoma of the alveolus of a Caucasian female. Keratin and involucrin markers present. Known mutations: p53 and p16. Cells are tumourigenic in athymic mice. Epidermal Growth Factor Receptor (EGFR) present.
- Research area: Cancer; Apoptosis and autophagy; Drug development; Genetics
- Cellosaurus ID: CVCL_2311
- Additional notes: STR-PCR Data: Amelogenin: X, X CSF1PO: 11,12 D13S317: 8,13 D16S539: 11 D5S818: 11,12 D7S820: 10,13 THO1: 6,7 TPOX: 8 vWA: 14,19
- For Research Use Only
Target Details
Application Details
- Application notes: STR-PCR Data: Amelogenin: X, X CSF1PO: 11,12 D13S317: 8,13 D16S539: 11 D5S818: 11,12 D7S820: 10,13 THO1: 6,7 TPOX: 8 vWA: 14,19
Handling
- Format: Frozen
- Growth medium: DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.4 micrograms/ml Hydrocortisone.
- Shipping conditions: Dry ice
Related Tools
References
- • Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.
- • Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.