BICR 78 Cell Line
- Name Eric Kenneth Parkinson
- Institute Cancer Research UK, Glasgow: The Beatson Institute
Tool name: BICR 78 Cell Line
Tool type: Cell Lines
Parental cell line:
Cancer type: Oral alveolus squamous carcinoma
Description: Adherent keratinocyte cell line derived from a squamous cell carcinoma of the oral alveolus of a Caucasian male. Keratin and involucrin markers present. Known mutations: p53, p16 and p14ARF. Cells are not tumourigenic in athymic mice.
Research area: Cancer ; Apoptosis and Programmed Cell Death ; Drug Discovery & Development ; Epigenetics & Nuclear Signalling
- For Research Use Only
- • Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.
- • Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.