CELL LINES

Contributor Information
- Name Eric Kenneth Parkinson
- Institute Cancer Research UK, Glasgow: The Beatson Institute
Tool Details
- Tool name: BICR 82 Cell Line
- Tool type: Cell Lines
- Organism: Human
- Tissue: Tongue
- Cancer type: Human Upper Jaw (Maxilla) Carcinoma
- Disease: Cancer
- Growth properties: Adherent
- Model: Tumour line
- Description: A keratinocyte cell line established from a squamous carcinoma of the upper jaw (maxilla) of a Caucasian male. Keratin and involucrin markers present. Known mutations: p53, p16 and p14ARF. Tumourigenicity in athymic mice not tested. Edington et al., 1995 must be cited and the cell line referred to by its original name.
- Research area: Cancer; Apoptosis and Programmed Cell Death; Drug Discovery & Development; Epigenetics & Nuclear Signalling
- Cellosaurus ID: CVCL_2316
- For Research Use Only
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References
- • Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.
- • Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.