D34 Cell Line
- Name Paul Harrison
- Institute Cancer Research UK, Glasgow: The Beatson Institute
Tool name: D34 Cell Line
Tool type: Cell Lines
Parental cell line:
Cancer type: Dysplasia, Leukoplakia
Description: D34 Cell Line is derived from a leukoplakia biopsy. The cell line was notable in its proliferative capacity, considered immortal after having completed more than 100 PDs (population doublings ) when maintained on a feeder layer of irradiated 3T3 fibroblasts. D34 was categorised as having a moderate dysplasia pathology.
Research area: Cancer ; Drug Discovery & Development
- For Research Use Only
- • McGregor et al. 2002. Cancer Res. 62(16):4757-66. PMID: 12183435.
- • Molecular changes associated with oral dysplasia progression and acquisition of immortality: potential for its reversal by 5-azacytidine.