CELL LINES
Contributor Information
- Name Leonard Franks
- Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
- Tool name: CMT 170 Cell Line
- Tool type: Cell Lines
- Organism: Mouse
- Tissue: Lung
- Cancer type: Lung carcinoma; Metastatic
- Disease: Cancer
- Growth properties: Tumorigenesis
- Model: Tumour line
- Description: The tumourigenic and metastatic CMT 170 murine cell line is sub-line of CMT 64 and an in vivo mouse tumourigenesis system to study the growth characteristics and metastasis of mouse tumour lines. it demonstrates stable growth characteristics and morphology in culture and in lung metastasis induced after subcutaneous inoculation of mice. CMT 170 was selected as a sub-line of CMT 64 for its increased metastatic ability.
- Research area: Cancer
- Production details: Mouse; CMT-170 isolated from primary alveogenic lung carcinoma tumour mass in C57BL/lcrf mouse, achieving stable morphology and growth rate in culture, similar to growth rate and morphology in primary tumour, and in lung metastasis induced after subcutaneous innoculation of mice.
- Cellosaurus ID: CVCL_B492
- For Research Use Only
Target Details
Application Details
Handling
- Format: Frozen
- Growth medium: DMEM with 10% FCS, supplemented with 20mM Hepes.
- Shipping conditions: Dry ice
Documentation
- Available on request
References
- • Franks et al. 1984. Br J Cancer. 49(4):423-9. PMID: 6324837.
- • Ultrastructural tumour differentiation and organ specificity in high and low metastatic lines from a mouse lung carcinoma.
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