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Contributor Information

  • Name Richard Edmondson
  • Institute Northern Institute For Cancer Research, Newcastle University

Tool Details

  • Tool name: NUOC-1 Cell Line
  • Alternate names: HGSC, high grade mixed ovarian cancer, epithelial ovarian cancer
  • Tool type: Cell Lines
  • Tool sub-type: Continuous
  • Parental cell line: Ascites of chemotherapy naive patient
  • Organism: Human
  • Tissue: Ovary
  • Cancer type: High Grade Ovarian Cancer
  • Disease: Cancer
  • Description: Epithelial ovarian cancer is diagnosed at late disease stage in more than 70% of patients. Ovarian cancer is the leading cause of gynaecological cancer mortality worldwide with a 5-year overall survival of 3039%. It has long been recognised by clinicians that ovarian cancer is a set of heterogeneous diseases. NUOC-1 cell line represents a novel ovarian cancer cell line derived from the ascites of a chemotherapy nave patient with a primary mixed endometrioid/ clear cell/ high grade serous ovarian cancer
  • Research area: Cancer ; Drug Discovery & Development

  • For Research Use Only

Target Details

Application Details

Handling

  • Format: Frozen
  • Growth medium: RPMI 1640 medium supplemented with 20% FCS, 20 mM L-glutamine and 1% penicillin and streptomycin
  • Storage conditions: Liquid Nitrogen
  • Shipping conditions: Dry ice
  • Mycoplasma free: Yes
  • Biosafety level: 1

Documentation

  • Available on request

References

  •   McCormick et al. 2017. Oncotarget. 8(16):26832-26844. PMID: 28460465.
  •   Functional characterisation of a novel ovarian cancer cell line, NUOC-1.