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Contributor Information

  • Name Irene Leigh
  • Institute Queen Mary University of London

Tool Details

  • Tool name: IC18 SCC Cell Line
  • Alternate names: SCC, Squamous cell carcinoma, IC18
  • Tool type: Cell Lines
  • Organism: Human
  • Tissue: Skin
  • Cancer type: Skin Cancer, Squamous Cell Carcinoma
  • Disease: Cancer
  • Model: Tumour line
  • Description: The SCC series represent primary, recurrent and metastatic carcinoma. Availability of such a series from the same individual will facilitate genetic analysis of the malignant process.
  • Research area: Cancer
  • Production details: Cutaneous SCC cell line from 81 year old male. Moderately defined primary tumour from the right ear with germline DNA from lymphocytes. Patient was immuno-competent and did not receive immune therapy

  • For Research Use Only

Target Details

  • Target: Squamous Cell Carcinoma

Application Details

Handling

  • Format: Frozen
  • Growth medium: Keratinocyte cell culture media supplemented with 10ng/ml EGF
  • Storage conditions: Liquid Nitrogen
  • Shipping conditions: Dry ice
  • Mycoplasma free: Yes
  • Biosafety level: 1

Documentation

  • Available on request

References

  •   Inman et al. 2018. Nat Commun. 9(1):3667. PMID: 30202019.
  •   The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature.