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Contributor Information

  • Name Irene Leigh
  • Institute Queen Mary University of London

Tool Details

  • Tool name: T10 SCC Cell Line
  • Alternate names: SCC, Squamous cell carcinoma, T1
  • Tool type: Cell Lines
  • Organism: Human
  • Tissue: Skin
  • Cancer type: Skin; Squamous Cell Carcinoma
  • Disease: Cancer
  • Model: Tumour line
  • Description: The SCC series represent primary, recurrent and metastatic carcinoma. Availability of such a series from the same individual will facilitate genetic analysis of the malignant process.
  • Research area: Cancer
  • Production details: Cutaneous SCC cell line from 60 year old male. Moderately defined primary tumour from the left shin with germline DNA from lymphocytes. Patient had a renal transplant and was treated with Azathioprine (A), Mycophenolate mofetil (MMF), Cyclosporine and Prednisolone. At time of lesional biopsy the patient had stopped receiving treatment of A and MMF.

  • For Research Use Only

Target Details

  • Target: Squamous Cell Carcinoma

Application Details


  • Format: Frozen
  • Growth medium: Keratinocyte medium: 3:1 V/V mixture of DMEM and Ham’s F12 supplemented with 10% FBS + and a cocktail of mitogens (0.4 μg/mL hydrocortisone, 1x10-8M or cholera toxin, 5 μg/mL transferrin, 2 x 10–11 M liothyronine 13 ng/ml, 5 μg/mL insulin, 10 ng/mL epidermal growth factor (EGF)
  • Storage conditions: Liquid Nitrogen
  • Shipping conditions: Dry ice
  • Mycoplasma free: Yes
  • Biosafety level: 1


  • Available on request


  •   Inman et al. 2018. Nat Commun. 9(1):3667. PMID: 30202019.
  •   The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature.