SVG-A Msh3 1.7X Cell Line
- Name Robert Lahue
- Institute National University of Ireland Galway ; Brown University
Tool name: SVG-A Msh3 1.7X Cell Line
Tool type: Cell Lines
Tool sub-type: Continuous
Parental cell line: Msh3-/- SVG-A Cell Line
Description: This cell line was derived from the SVG-A Msh3-/- (knock-out generated by CRISPR)) cell line whereby the DNA mismatch repair protein Msh3 expression has been reinstated.
Research area: DNA Damage and Repair ; Neurobiology
Additional notes: Cancer Research Technology Limited (trading research tools as CancerTools.org) has been granted a non-exclusive license to the CRISPR-Cas9 technology by ERS Genomics Ltd under the patent rights listed here: https://www.cancertools.org/tool-faqs#hs_cos_wrapper_widget_1649861453796 This license from ERS Genomics Ltd allows CancerTools.org to develop and commercialise CRISPR-Cas9 modified cell lines for research use only. CancerTools.org can provide these modified CRISPR-Cas9 cell lines to companies under a label-use only license
- For Research Use Only
- • Keogh et al. 2017. MutS? abundance and Msh3 ATP hydrolysis activity are important drivers of CTGCAG repeat expansions. Nucleic Acids Res. 2017 Sep 29
- • 45(17):10068-10078.