CELL LINES
Contributor Information
- Name Robert Lahue
- Institute National University of Ireland Galway ; Brown University
Tool Details
- Tool name: SVG-A Msh3 1.7X Cell Line
- Tool type: Cell Lines
- Tool sub-type: Continuous
- Parental cell line: Msh3-/- SVG-A Cell Line
- Organism: Human
- Tissue: Brain
- Description: This cell line was derived from the SVG-A Msh3-/- (knock-out generated by CRISPR)) cell line whereby the DNA mismatch repair protein Msh3 expression has been reinstated.
- Research area: DNA Damage and Repair; Neurobiology
- Additional notes: CRISPR edited cells. Cancer Research Technology Limited (trading research tools as Ximbio) has been granted a non-exclusive license to the CRISPR-Cas9 technology by ERS Genomics Ltd under the patent rights listed here. This license from ERS Genomics Ltd allows Ximbio to develop and commercialise CRISPR-Cas9 modified cell lines for research use only. Ximbio can provide these modified CRISPR-Cas9 cell lines to companies under a label-use only license.
- For Research Use Only
Target Details
Application Details
- Application notes: Cancer Research Technology Limited (trading research tools as CancerTools.org) has been granted a non-exclusive license to the CRISPR-Cas9 technology by ERS Genomics Ltd under the patent rights listed here: https://www.cancertools.org/tool-faqs#hs_cos_wrapper_widget_1649861453796 This license from ERS Genomics Ltd allows CancerTools.org to develop and commercialise CRISPR-Cas9 modified cell lines for research use only. CancerTools.org can provide these modified CRISPR-Cas9 cell lines to companies under a label-use only license
Handling
- Format: Frozen
- Growth medium: DMEM supplemented with 10% FBS
- Storage conditions: Liquid Nitrogen
- Shipping conditions: Dry ice
- Mycoplasma free: Yes
- Biosafety level: 1
Documentation
- Available on request
Related Tools
References
- • Keogh et al. 2017. MutS? abundance and Msh3 ATP hydrolysis activity are important drivers of CTG
- • 45(17):10068-10078.
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