Product Image

Contributor Information

  • Name Steven Grant
  • Institute Virginia Commonwealth University

Tool Details

  • Tool name: Human Imatinib Mesylate-Resistant Leukemia Cell Line
  • Tool type: Cell Lines
  • Tool sub-type: Continuous
  • Parental cell line: BV173
  • Organism: Human
  • Cancer type: Acute Lymphoblastic Leukemia (Ph+ ALL); Chronic Myelogenous Leukemia (CML)
  • Disease: Cancer
  • Description: The human ALL cell line, named BV173, was altered to be imatinib resistant and contains the most frequently observed mutation (E255K) responsible for drug resistance in patients.
  • Research area: Cancer

  • For Research Use Only

Target Details

Application Details

Handling

  • Format: Frozen
  • Growth medium:
  • Shipping conditions: Dry ice

Documentation

  • Available on request

References

  •   Cormack et al. 1992. J Mol Biol. 228(4):1078-90. PMID: 1474579.
  •   Structural requirements for the processing of Escherichia coli 5 S ribosomal RNA by RNase E in vitro.