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Contributor Information

  • Name Aloysius Klingelhutz
  • Institute The University of Iowa

Tool Details

  • Tool name: HFK clone 22 cell line
  • Tool type: Cell Lines
  • Organism: Human
  • Tissue: Foreskin
  • Disease: Pathogenesis and Inflammation Studies
  • Growth properties: foreskin keratinocytes
  • Model: Immortalised Line
  • Conditional: No
  • Description: useful for researchers studying cancer/infection biology and pathogenesis
  • Production details: Immortalized with TERT

  • For Research Use Only

Target Details

  • Target: foreskin keratinocytes; Used as an immortal neonatal human skin keratinocyte line for pathogenesis and inflammation studies, transformation

Application Details

  • Application notes: useful for researchers studying cancer/infection biology and pathogenesis

Handling

  • Format: Frozen
  • Storage conditions: Liquid Nitrogen
  • Shipping conditions: Dry ice
  • Mycoplasma free: Yes
  • Biosafety level: 1

Documentation

  • Available on request

References

  •   James et al. 2006. Int J Cancer. 119(8):1878-85. PMID: 16708385.
  •   HPV16-E6 associated hTERT promoter acetylation is E6AP dependent, increased in later passage cells and enhanced by loss of p300.