CELL LINES
Contributor Information
- Name Lawrence Pfeffer
- Institute The University of Tennessee Health Science Center
Tool Details
- Tool name: STAT2-Defective Mutant Daudi (RST2) cell line
- Tool type: Cell Lines
- Tool sub-type: Continuous
- Parental cell line: Human Daudi Burkitt Lymphoma cell line
- Organism: Human
- Tissue: Blood
- Cancer type: Blood cancer
- Disease: Cancer
- Model: Transgenic
- Description: This cell line can be used to study drug resistance developed after treatment with interferon. Interferon therapy has been proved as a successful treatment for various types of cancer, however it develops resistance in patients. This cell line was not affected by the antiviral, antiproliferative, and gene-inducing actions of IFN.
- Research area: Cancer
- Production details: Isolated from IFN-sensitive Daudi cell line by growth in the continuous presence of IFN
- For Research Use Only
Target Details
Application Details
Handling
- Format: Frozen
- Growth medium: RPMI1640 and 10% defined calf serum; Subculture 1:4 twice a week, maintain 1 and 10X10^5 cells/mL
- Shipping conditions: Dry ice
Documentation
Related Tools
References
- • Schmeisser et al. 2013. Autophagy. 9(5):683-96. PMID: 23419269.
- • Du et al. 2009. J Biol Chem. 284(41):27808-15. PMID: 19687011.
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