CELL LINES
Contributor Information
- Name Varda Rotter
- Institute Weizmann Institute of Science
Tool Details
- Tool name: hTERT PF179T CAF cell line
- Tool type: Cell Lines
- Tool sub-type: Continuous
- Parental cell line: PF179T
- Organism: Human
- Tissue: Fibroblast
- Cancer type: Prostate
- Disease: Cancer
- Growth properties: Fibroblast
- Model: Tumour line
- Conditional: Yes
- Description: Fibroblasts located adjacent to the tumour (cancer-associated fibroblasts (CAFs)) that constitute a large proportion of the cancer-associated stroma facilitate the transformation process.This cell line can be used to help to understand the biological behaviour of CAFs in cells isolated from a human prostate tumour.
- Research area: Cancer
- Production details: Primary human prostate fibroblasts (PFs) (designated PF179; 179, patient number) were isolated from a prostatectomy specimen, marginal and distal to the prostate tumor. (PMID: 18842679).
- Cellosaurus ID: CVCL_JL59
- For Research Use Only
Target Details
- Target: Prostate Cancer
Application Details
Handling
- Format: Frozen
- Growth medium: Recommend growth in minimum essential medium supplemented with 10% fetal calf serum, 2 mM l-glutamine, 1 mM sodium pyruvate and antibiotics. Publication PMID: 18842679
- Storage conditions: Liquid Nitrogen
- Shipping conditions: Dry ice
- Mycoplasma free: Yes
- Biosafety level: 1
Documentation
- Available on request
Related Tools
References
- • Madar et al. 2009. Carcinogenesis. 30(1):20-7. PMID: 18842679.
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