Bovine Type II Alveolar Epithelial (B2AE) cell line
- Name Diane Lee
- Institute University of Surrey
Tool name: Bovine Type II Alveolar Epithelial (B2AE) cell line
Tool type: Cell Lines
Growth properties: Cobblestone. Fixed (2D), 3D (matrigel) or air-liquid interface (ALI)
Model: Immortalised Line
Description: Differentiates into Alveolar Type I (ATI)-like cells when cultured at air-liquid interface, generating a mixed population of Alveolar Type II (ATII) and ATI in a pseudostratified epithelial cell layer. Used in co-culture with bovine pulmonary arterial endothelial cells as a model of the bovine alveolus.
Research area: Immunology ; Other
Production details: Generated by the lentiviral transduction of Bmi1 and hTERT into primary bovine alveolar type II epithelial cells at passage 1. Proliferation rate as for primary.
- For Research Use Only