Cat. #160438
UM-UC-7 (Human transitional cell carcinoma of the bladder) cell line
Cat. #: 160438
Unit size: 1x10^6 cells / vial
Organism: Human
Tissue: Bladder
Disease: Cancer
Model: Tumourigenic cell line
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: H. Grossman ; Anita Sabichi
Institute: University of Michigan
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: UM-UC-7 (Human transitional cell carcinoma of the bladder) cell line
- Alternate name: UMUC7; University of Michigan-Urothelial Carcinoma-7
- Cancer: Genitourinary cancer
- Cancers detailed: Human bladder transitional cell carcinoma
- Research fields: Cancer
- Organism: Human
- Tissue: Bladder
- Disease: Cancer
- Growth properties: Adherent
- Model: Tumourigenic cell line
- Description: UM-UC-7 is a human transitional cell carcinoma cell line derived from a male bladder cancer patient. The UM-UC panel of urothelial carcinoma is a diverse range of 11 patient derived cell lines developed by the university of Michigan that have been well-categorised in the literature. These cells were assessed for their susceptibility to adenoviral mediated gene delivery, tumour growth in nude mice and differences in genetic alterations.
Handling
- Format: Frozen
- Growth medium: Cells were grown in EMEM (EBSS) + 2mM Glutamine + 1% Non Essential Amino Acids (NEAA) + 10% Foetal Bovine Serum (FBS).
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
- Subculture routine: Split sub-confluent cultures (70-80%) 1:3 to 1:6 i.e. seeding at 2-4x10,000 cells/cm2; using 0.05% trypsin/EDTA; 5% CO2, 37°C. Doubling time approximately 19 hours.
Related Tools
- Related tools: UM-UC-1 (Human bladder transitional cell carcinoma) cell line ; UM-UC-3 (Human bladder transitional cell carcinoma) cell line ; UM-UC-4 (Human adenocarcinoma lymph node metastasis) cell line ; UM-UC-5 (Human squamous cell carcinoma of the bladder) cell line ; UM-UC-9 (Human transitional cell carcinoma of the bladder) cell line ; UM-UC-10 (Human transitional cell carcinoma of the bladder) cell line
References
- Grossman et al. 1986. J Urol. 136(5):953-9. PMID: 3761468
- Park et al. 2008. J Natl Cancer Inst. 100(19):1401-11. PMID: 18812553
- Guo et al. 2013. J Pathol. 230(1):17-27. PMID: 23401075
- Allory et al. 2014. Eur Urol. 65(2):360-6. PMID: 24018021
- Earl et al. 2015. BMC Genomics. 16:403. PMID: 25997541
- Zuiverloon et al. 2018. Bladder Cancer. 4(2):169-83. PMID: 29732388
