UM-RC-3 (Human renal carcinoma) cell line
- Name H. Grossman
- Institute University of Michigan
Tool name: UM-RC-3 (Human renal carcinoma) cell line
Tool type: Cell Lines
Parental cell line:
Cancer type: Human renal carcinoma
Description: UM-RC-3 are a renal carcinoma cell line, established in long term culture, from surgically obtained renal carcinoma specimens of patients who underwent nephrectomy. This patient had metastatic disease at the time of nephrectomy. Initial work suggests these cells grow well in primary culture but life expectancy is limited to less than 10 passages. These cells were evaluated for their ability to form tumors in nude mice and were confirmed to produced clear cell tumors. UM-RC-3 cells demonstrated no autologous reactivity in Protein A assays in low passage number cells but did in higher passage numbers. These cells are adherent and display a loss of contact inhibition. Doubling time is approximately 29 hours.
Research area: Cancer
- For Research Use Only
- • Grossman et al. 1985. J Surg Oncol. 28(3):237-44. PMID: 4038766.