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Contributor Information

  • Name H. Grossman
  • Institute University of Michigan

Tool Details

  • Tool name: UM-RC-6 (Human renal carcinoma) cell line
  • Tool type: Cell Lines
  • Parental cell line:
  • Organism: Human
  • Tissue: Bladder
  • Cancer type: Human renal carcinoma
  • Disease: Cancer
  • Description: UM-RC-6 are a renal carcinoma cell line, established in long term culture, from surgically obtained renal carcinoma specimens of patients who underwent nephrectomy. Initial work suggests these cells grow well in primary culture but life expectancy is limited to less than 10 passages. These cells were evaluated for their ability to form tumors in nude mice, however, no tumor development was observed. UM-RC-6 cells demonstrated no autologous reactivity in Protein A assays in low passage number cells but did in higher passage numbers. These cells are adherent and display a loss of contact inhibition. Doubling time is approximately 43 hours.
  • Research area: Cancer

  • For Research Use Only

Target Details

Application Details

Handling

  • Format: Frozen
  • Growth medium: Cells were grown in Eagle's Minimum Essential Medium (EMEM) containing 1% nonessential amino acids, 2mM glutamine, 100U/ml penicillin, 100ug/ml streptomycin and 10% Fetal Bovine Serum (FBS).
  • Shipping conditions: Dry ice

Documentation

  • Available on request

References

  •   Grossman et al. 1985. J Surg Oncol. 28(3):237-44. PMID: 4038766.