Human uveal melanoma C918 cell line
Uveal melanoma is a rare, but deadly, cancer of of the eye involving the uvea (iris, ciliary body, or choroid). Tumors arise from melanocytes mostly in the uvea, but can…
Contributors
| Inventor | Institute |
|---|---|
| Karla Daniels | The University of Iowa |
| Cat. #: | 160513 |
|---|---|
| Tool sub type: | Primary |
| Unit size: | 1×10^6 cells / vial |
| Organism: | Human |
| Tissue: | Eye |
| Gender: | Male |
| Model: | Cancer Model |
| Product description: | Uveal melanoma is a rare, but deadly, cancer of of the eye involving the uvea (iris, ciliary body, or choroid). Tumors arise from melanocytes mostly in the uvea, but can also arise from the conjunctiva and other sites within the eye. This cell line was derived from primary choroidal melanomas. This cell line is positive for type VI collagen via IHC. |
|---|---|
| Gender: | Male |
| CRISPR: | Yes |
| Conditional: | No |
| Cellosaurus ID: | CVCL_8471 |
| Parental cell line: | Derived from primary human uveal melanoma |
| Format: | Frozen |
|---|---|
| Shipping conditions: | Dry ice |
| Growth medium: | RPMI 1640 with 1% insulin-selenium-transferrin, 10mM HEPES, supplemented with 5% heat-inactive FBS, 60 IU/mL Penicillin and 100 IU/mL Streptomycin, and 100mg/L L-Glutamate |
| Mycoplasma free: | Yes |
| References: |
Dutton-Regester et al., 2012. Mol Cancer Ther. 11 (4): 888–897. PMID: 22383533 Folberg et al. 2008. Invest Ophthalmol Vis Sci. 49(11):4697-701. PMID: 18689700. • Bittner M et al. 2000. Nature 406(6795):536-40. PMID: 10952317. Daniels et al. 1996. Lab Invest. 75(1):55-66. PMID: 8683940. |
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