CELL LINES

Contributor Information
- Name Karla Daniels
- Institute The University of Iowa
Tool Details
- Tool name: Human uveal melanoma M619 cell line
- Tool type: Cell Lines
- Tool sub-type: Primary
- Parental cell line: Derived from primary human uveal melanoma
- Organism: Human
- Tissue: Eye
- Cancer type: Eye cancer
- Disease: Cancer
- Model: Cancer Model
- Conditional: No
- Description: Uveal melanoma is a rare, but deadly, cancer of of the eye involving the uvea (iris, ciliary body, or choroid). Tumors arise from melanocytes mostly in the uvea, but can also arise from the conjunctiva and other sites within the eye. This cell line was derived from primary choroidal melanomas. This cell line is positive for type VI collagen via IHC.
- Research area: Cancer; Drug development
- Cellosaurus ID: CVCL_8472
- For Research Use Only
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References
- • Folberg et al. 2008. Invest Ophthalmol Vis Sci. 49(11):4697-701. PMID: 18689700.
- • Folberg et al. 2007. Invest Ophthalmol Vis Sci. 48(7):2967-74. PMID: 17591861.
- • Daniels et al. 1996. Lab Invest. 75(1):55-66. PMID: 8683940.