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Contributor Information

  • Name Jose Luis Pedraz ; JesĂşs Ciriza ; Laura Saenz del Burgo
  • Institute University of the Basque Country (EHU)

Tool Details

  • Tool name: Sonic hedgehog-expressing D1-MSC cell line
  • Alternate names: SHH
  • Tool type: Cell Lines
  • Tool sub-type: Continuous
  • Parental cell line: D1-MSC
  • Organism: Mouse
  • Tissue: Bone Marrow
  • Cancer type: Skeletal development
  • Disease: Cancer
  • Description: Sonic hedgehog is a protein that plays a key role in the development of animals from insects to mammals. In vertebrates, it is involved in organogenesis, including the growth of digits on limbs and the organization of the brain. Sonic hedgehog is also active in adults; for example, it controls the proliferation of adult stem cells and has been implicated in the development of some cancers. Sonic hedgehog-expressing D1-MSC can be used for the study of promotion of stem cells proliferation in vivo and in vitro by the release of the transgenic Sonic hedgehog.
  • Research area: Developmental Biology ; Stem Cell Biology

  • For Research Use Only

Target Details

Application Details

Handling

  • Format: Frozen
  • Growth medium: DMEM supplemented with 10% FCS and P/S
  • Shipping conditions: Dry ice

Documentation

  • Available on request