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Contributor Information

  • Name Carmel McConville
  • Institute University of Birmingham

Tool Details

  • Tool name: BCH-N-LR Neuroblastoma cell line
  • Tool type: Cell Lines
  • Tool sub-type: Primary
  • Parental cell line:
  • Organism: Human
  • Tissue: Adrenal Gland
  • Gender: Male
  • Cancer type: Neuroblastoma
  • Disease: Cancer
  • Application: Neuroblastoma cells have been used for the following: - Investigation of metabolic profiles generated by in vitro H MRS - Characterisation of genetic pathways - Discovery of epigenetically deregulated genes during neuroblastoma tumorigenesis, using genome wide DNA methylation analysis - Functional investigation of MEGF10 knockdown
  • Description: Neuroblastoma is the most common extracranial solid malignancy in children. The disease possesses a broad range of clinical phenotypes with widely varying prognoses. Standard clinical and pathological assessments do not always differentiate reliably between tumor subtypes and, therefore, genetic markers are now playing an increasingly important role in treatment decisions.
  • Research area: Cancer

  • For Research Use Only

Target Details

Application Details

  • Application: Neuroblastoma cells have been used for the following: - Investigation of metabolic profiles generated by in vitro H MRS - Characterisation of genetic pathways - Discovery of epigenetically deregulated genes during neuroblastoma tumorigenesis, using genome wide DNA methylation analysis - Functional investigation of MEGF10 knockdown

Handling

  • Format: Frozen
  • Growth medium: Growth medium: DME/F12+15% fetal calf serum + glutamine + non-essential amino acids.
  • Shipping conditions: Dry ice

Documentation

  • Available on request