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Contributor Information

  • Institute LeukoCom

Tool Details

  • Tool name: HEK293-CEACAM6-Fc cell line
  • Alternate names: Carcinoembryonic antigen-related cell adhesion molecule 6, CD66c, Cluster of Differentiation 66c
  • Tool type: Cell Lines
  • Tool sub-type: Continuous
  • Parental cell line: HEK293
  • Organism: Human
  • Tissue: Kidney
  • Growth properties: Adherent
  • Model: Transgenic
  • Conditional: No
  • Description: CEACAM-6 is expressed by granulocytes and their precursors. Activation enhances surface expression by mobilizing CEACAM-6 from storage in azurophilic granules. It often shows aberrant expression in acute lymphocytic leukaemia's. CEACAM-6 is also expressed in epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas and hyperplastic polyps. Over-expression confers resistance to adhesion-related apoptosis (anoikis) in tumour cells
  • Research area: Cancer; Cell biology
  • Production details: Overexpression of human CEACAM6-Fc Chimera Protein

  • For Research Use Only

Target Details

  • Target: CEACAM6

Application Details

Handling

  • Format: Frozen
  • Growth medium: DMEM + 10% FBS
  • Storage conditions: Liquid Nitrogen
  • Shipping conditions: Dry ice
  • Mycoplasma free: Yes
  • Biosafety level: 1

Documentation

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