TOV-21G cell line

Spontaneous immortalised epithelial ovarian cancer cell line

Contributors

Inventor Institute
Anne-Marie Mes-Masson and Diane Provencher Centre Hospitalier de L’université de Montréal
Cat. #: 161764
Cancer types: Gynaecologic cancer
Research Fields: Cancer
Organism: Human
Tissue: Derived from solid tumors of ovarian cancer patient
Gender: Female
Cancer Types In Detail: Clear cell carcinoma
Primary citation: Provencher et al. 2000. In Vitro Cell.Dev.Biol.-Animal 36(6):357-61. PMID:10949993
Alternate name: TOV-21G
Product description: Spontaneous immortalised epithelial ovarian cancer cell line derived from a patient never exposed to chemotherapy or radiation therapy. Cell line retains cahracteristics of the original epithelial ovarian cancers from which it was derived.
CRISPR: No
Cellosaurus ID: CVCL_3613
Receptors of note: No
Gender: Female
Growth medium: OSE medium consisting of 50:50 medium 199:105 (Sigma), with 2.5 μg/mL amphotericin B and 50 μg/mL gentamicin
References:

Yang et al. 2025. Nat Commun.16(1):2071. PMID: 40021646

Brodeur et al. 2021. Sci Rep. 14.11(1):18183. PMID: 34521878

Beltran et al. 2014. Clin Cancer Res. 20(11):2947-58. PMID: 24727326

Loganathan et al. 2012. PLoS One. 7(8):e43577. PMID: 22952709

Kandala & Srivastava. 2012. BMC Med. 10:9. PMID: 22280969

Provencher et al. 2000. In Vitro Cell Dev Biol Anim. (36): 357–361. PMID:10949993

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