MEDIA
Contributor Information
- Name Madeline Torres-Lugo
- Institute University of Puerto Rico
- Primary citation Lizana-Vasquez et al. Polymers (Basel) 14(20): 4379. PMID 36297960
Tool Details
- Tool name: Synthetic Matrixes for Cell Culture and Manufacture
- Tool type: Other: Synthetic Matrix
- Purpose: Create a large-scale manufacturing platform for cell growth
- Application: Hydrogel 3D Scaffolds, Tissue Engineering, Cell or cytotherapy, Immunontherapy, Large scale manufacturing of living cells, Cancer cell aggregates
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Description: Scaleable manufacturing platform for cell growth using synthetic materials capable of encapsulating cells during culture while allowing removal without mechanical manipulation. The ability to monitor cell growth by microscopy and incorporate molecular cues is also possible due to the platforms transparency.
Developed from a combination of three monomers resulting in polymer structure. p(NiPAAm-co-4-VPBA-co-PEGMMA) thermo-responsibve tetropolymers were synthesized yb a free radical polymerization method - Formulation: Poly(N-isopropylacrylamid), vinyl phenylboronic acid (VPBA), and polethylene glycol monomethyl ether mono methacrylate (PEGMMA)
- Research area: Cell biology; Immuno-oncology
- For Research Use Only
Target Details
Application Details
- Application: Hydrogel 3D Scaffolds, Tissue Engineering, Cell or cytotherapy, Immunontherapy, Large scale manufacturing of living cells, Cancer cell aggregates
Handling
Documentation
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