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Contributor Information

  • Name John Marshall
  • Institute Queen Mary University of London

Tool Details

  • Tool name: Integrin AvB6 inhibiting Peptide
  • Tool type: Proteins
  • Tool sub-type: Inhibitor
  • Source: HEK293
  • Function: Inhibitor
  • Description: av?6 is a major new target for molecular-specific imaging and therapy of cancer. It is expressed only on epithelia and then usually only during processes of tissue remodelling; these include wound healing, chronic inflammation, and cancer. The av?6 inhibiting peptide could not only permit diagnostic imaging, but also to deliver anticancer therapy specifically to tumour cells while sparing local normal tissues.
  • Research area: Cancer ; Cell Structure and Motility
  • Purpose: Inhibitor

  • For Research Use Only

Target Details

  • Target: Integrin AvB6 inhibiting peptide

Application Details

Handling

  • Shipping conditions: Dry Ice

Documentation

  • Available on request

References

  •   Saha et al. 2010. J Pathol. 222(1):52-63. PMID: 20629113.
  •   High-resolution in vivo imaging of breast cancer by targeting the pro-invasive integrin alphavbeta6.