Integrin AvB6 inhibiting Peptide
- Name John Marshall
- Institute Queen Mary University of London
Tool name: Integrin AvB6 inhibiting Peptide
Tool type: Proteins
Tool sub-type: Inhibitor
Description: av?6 is a major new target for molecular-specific imaging and therapy of cancer. It is expressed only on epithelia and then usually only during processes of tissue remodelling; these include wound healing, chronic inflammation, and cancer. The av?6 inhibiting peptide could not only permit diagnostic imaging, but also to deliver anticancer therapy specifically to tumour cells while sparing local normal tissues.
Research area: Cancer; Cell biology
Animal free: Yes
- For Research Use Only
- • Saha et al. 2010. J Pathol. 222(1):52-63. PMID: 20629113.
- • High-resolution in vivo imaging of breast cancer by targeting the pro-invasive integrin alphavbeta6.