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Contributor Information

  • Name Prakash Lingasamy ; Tambet Teesalu
  • Institute University of Tartu

Tool Details

  • Tool name: PL2 Peptide
  • Alternate names: PL2, Oncofetal fibronectin (FN-EDB) specific peptide
  • Tool type: Proteins
  • Tool sub-type: Synthetic Peptide
  • Sequence: TSKQNSR
  • Expression system: Synthetic
  • Function: Marker
  • Description: Oncofetal fibronectin (FN-EDB) is not present in the extracellular matrix of adult tissues but it is up-regulated in tumours and malignant tissues. It has previously been used as a target for antibody-based therapies. The PL2 specific peptide has enhanced affinity to bind to FN-EDB so may be useful as an affinity ligand for delivery of diagnostic compounds into solid tumours.
  • Research area: Cancer ; Extracellular Matrix
  • Purpose: Marker

  • For Research Use Only

Target Details

  • Target: Oncofetal fibronectin (FN-EDB)

Application Details

Handling

  • Storage conditions:
  • Shipping conditions: Dry Ice

Documentation

  • Available on request