PROTEINS
Contributor Information
- Name Prakash Lingasamy ; Tambet Teesalu
- Institute University of Tartu
Tool Details
- Tool name: PL2 Peptide
- Alternate names: PL2, Oncofetal fibronectin (FN-EDB) specific peptide
- Tool type: Proteins
- Tool sub-type: Synthetic Peptide
- Sequence: TSKQNSR
- Cellular/ tissue localisation: PL2 is specific to oncofetal fibronection Extra Domain-B
- Expression system: Synthetic
- Function: Marker
- Description: Oncofetal fibronectin (FN-EDB) is not present in the extracellular matrix of adult tissues but it is up-regulated in tumours and malignant tissues. It has previously been used as a target for antibody-based therapies. The PL2 specific peptide has enhanced affinity to bind to FN-EDB so may be useful as an affinity ligand for delivery of diagnostic compounds into solid tumours.
- Research area: Cancer; Extracellular Matrix
- Purpose: Marker
- For Research Use Only
Target Details
- Target: Oncofetal fibronectin (FN-EDB)
Application Details
Handling
- Shipping conditions: Dry Ice
Documentation
- Available on request
.svg)
.svg)
