PROTEINS
Contributor Information
- Name Prakash Lingasamy ; Tambet Teesalu
- Institute University of Tartu
Tool Details
- Tool name: PL3 Peptide
- Alternate names: PL3, Tenascin-C C domain specific peptide
- Tool type: Proteins
- Tool sub-type: Synthetic Peptide
- Sequence: AGRGRLVR
- Cellular/ tissue localisation: PL3 is specific to tenascin-C C domain (TNC-C)
- Expression system: Synthetic
- Function: Marker
- Description: Tenascin-C C domain (TNC-C) is not present in the extracellular matrix of adult tissues but it is up-regulated in tumours and malignant tissues. It has previously been used as a target for antibody-based therapies. PL3 is a specific peptide which has enhanced affinity to bind to TNC-C so PL3 may be useful as an affinity ligand for delivery of diagnostic compound into solid tumours.
- Research area: Cancer; Extracellular Matrix
- Purpose: Marker
- For Research Use Only
Target Details
- Target: Tenascin-C C domain (TNC-C)
Application Details
Handling
- Shipping conditions: Dry Ice
Documentation
- Available on request
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