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Contributor Information

  • Name Ron Grigg
  • Institute University of Leeds

Tool Details

  • Tool name: HDAC2/3 inhibitor MI-192 Small Molecule (Tool Compound)
  • Molecular formula: C24H21N3O2.HCl
  • Tool type: Small molecules
  • Tool sub-type: Inhibitor
  • Purpose: Inhibitor
  • Description: MI-192 is a novel benzamide-based compound with marked selectivity for the class I enzymes, HDAC2 (histone-deacetylase 2) and HDAC3 (histone-deacetylase 3). MI-192 is also a histone-deacetylase (HDAC)-3 selective inhibitor. MI-192 might have potential in the treatment of rheumatoid arthritis, and HDAC-selective inhibition may improve the therapeutic margin of safety. Studies in various cancer cell lines have also revealed that MI-192 might be a potential therapeutic agent for use in leukaemia.
  • Research area: Apoptosis and Programmed Cell Death ; Cancer ; Plant Science

  • For Research Use Only

Target Details

  • Target: HDAC2/3

Application Details


  • Purity: 419.91 g/mol
  • Solubility: DMSO
  • Storage conditions: Ambient
  • Shipping conditions: Dry Ice


  • Available on request


  •   WO2013005049 PMID: 22818799