SMALL MOLECULES

Contributor Information
- Name Simak Ali
- Institute Imperial College London
Tool Details
- Tool name: CDK inhibitor BS-194 Small Molecule (Tool Compound)
- Molecular formula: C20H27N5O3
- Tool type: Small molecules
- Tool sub-type: Inhibitor
- Purpose: Inhibitor
- Molecular weight of the target: 385.5
- Description: BS-194 is a selective and potent CDK inhibitor, which inhibits CDK2, CDK1, CDK5, CDK7, and CDK9.
- Research area: Cancer; Epigenetics & Nuclear Signalling; Gene Expression
- Selectivity: CDK1, CDK2, CDK7, and CDK9
- IUPAC: (2S,3S)-3-(7-(benzylamino)-3- isopropylpyrazolo[1,5-a]pyrimidin-5- ylamino)butane-1,2,4-triol
- IC50: CDK2, CDK1, CDK5, CDK7, and CDK9 (IC50=3, 30, 30, 250, and 90 nmol/L, respectively)
- For Research Use Only
Related Tools
References
- • J. Med. Chem. 2010, 53, 85088522