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Contributor Information

  • Institute AstraZeneca

Tool Details

  • Tool name: [Src/Abl1] Inhibitor AZD0424 Small Molecule Tool Compound
  • Alternate names: Src/Abl1 Kinase Inhibitor AZD424
  • Tool type: Small molecules
  • Tool sub-type: Inhibitor
  • Purpose: Inhibitor
  • Description: Potent and selective inhibitor of Src/Abl1 kinases showing additional activity against other Src family kinase members including Yes, Fgr, Lck, Hck, Fyn and Blk. Suggested application in Alzheimer's disease, schizophrenia and treatment of alcoholism; Saracatinib, a related Src inhibitor has been used in clinical trials for Alzheimer's disease and alcoholism.
  • Research area: Cancer ; Cell Signaling & Signal Transduction ; Other

  • For Research Use Only

Target Details

Application Details


  • Purity:
  • Solubility:
  • Storage conditions: Cold storage required (2-8°C)
  • Shipping conditions: Dry Ice


  • Available on request


  •   Woodcock et al. 2018. Br J Cancer. 118(6):770-776. PMID: 29438361.
  •   A first-in-human phase I study to determine the maximum tolerated dose of the oral Src/ABL inhibitor AZD0424.