Glycated HSA Rhodamine Boronic Acid small molecule (tool compound)
- Name Marta P. Pereira Morais
- Institute University of Bath
Tool name: Glycated HSA Rhodamine Boronic Acid small molecule (tool compound)
Alternate names: AGEs
Tool type: Small molecules
Description: Protein glycation, also known as non-enzymatic glycosylation, has been implicated in various disease states and is therefore an important biomarker for ageing and age-related chronic diseases such as diabetes, cardiovascular diseases, autoimmune diseases, cancer, and Alzheimer's disease. However their analysis is challenging due to the complexity of the protein-carbohydrate adducts. Fluorescent boronic acids like these enable the detection and identification of individual glycated proteins in complex samples through gel electrophoresis.
Research area: Cancer ; Cell Type or Organelle Marker ; Fluorescent Cell Imaging
- For Research Use Only
- • Pereira Morais et al. 2013. Sci Rep. 3:1437. PMID: 23531746.