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Contributor Information

  • Name Marta P. Pereira Morais
  • Institute University of Bath

Tool Details

  • Tool name: Glycated HSA Rhodamine Boronic Acid small molecule (tool compound)
  • Alternate names: AGEs
  • Tool type: Small molecules
  • Description: Protein glycation, also known as non-enzymatic glycosylation, has been implicated in various disease states and is therefore an important biomarker for ageing and age-related chronic diseases such as diabetes, cardiovascular diseases, autoimmune diseases, cancer, and Alzheimer's disease. However their analysis is challenging due to the complexity of the protein-carbohydrate adducts. Fluorescent boronic acids like these enable the detection and identification of individual glycated proteins in complex samples through gel electrophoresis.
  • Research area: Cancer ; Cell Type or Organelle Marker ; Fluorescent Cell Imaging

  • For Research Use Only

Target Details

  • Target: Advanced Glycation Endproducts (AGE); specifically Glycated Human Serum Albumin (HSA). Also binds ApoA-I protein.

Application Details

Handling

  • Purity:
  • Solubility:
  • Storage conditions:
  • Shipping conditions: Dry Ice

Documentation

  • Available on request

References

  •   Pereira Morais et al. 2013. Sci Rep. 3:1437. PMID: 23531746.