Isobenzofuran analog of sclerophytin A (8b) small molecule
- Name Matt McIntosh
- Institute University of Arkansas, Fayetteville
Tool name: Isobenzofuran analog of sclerophytin A (8b) small molecule
Tool type: Small molecules
Description: Naturally occurring products 2, 11 cyclized cembranoids have been shown to inhibit the growth of KB3 nasopharyngeal carcinoma. The standard cancer cell line used to test for chemotherapy effectiveness. The bicyclic hydroisobenzofuran is the beneficial compounds that are naturally occurring in 2, 11 cyclized cembranoids. This compound has shown inhibition of growth of KB3 cancer test cells and could be used in cancer and antibiotics research.
Research area: Cancer
IC50: 30 ÎźM
- For Research Use Only
- • Bateman et al. 2009. Bioorg Med Chem Lett. 19(24):6898-901. PMID: 19896844.