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Contributor Information

  • Name Osvaldo Cox (Retired), Beatriz Zayas
  • Institute Universidad Ana G. Mendez

Tool Details

  • Tool name: ABQ-48 small molecule
  • Molecular formula: C22H38CIN3
  • Tool type: Small molecules
  • Tool sub-type: Inhibitor
  • Molecular weight of the target: 359.8514
  • Application: cell hypoxia marker; fluorescence-based multiplex ELISA
  • Description: Inhibitor of growth in several cancer cell line models. This small molecule can also be used as a cell hypoxia marker in 2D and 3D colon cancer cell models.
  • Research area: Cancer; Fluorescent Cell Imaging
  • IUPAC: 7-benzyl-3-aminobenzimidazo[3,2-a]quinolinium chloride
  • IC50: 23 uM (A431 cells), 8.6 uM (Tk6 cells), 23uM (Toledo cells)

  • For Research Use Only

Target Details

  • Target molecular weight: 359.8514

Application Details

  • Application: cell hypoxia marker; fluorescence-based multiplex ELISA

Handling

  • Purity: 359.8514 g/mol
  • Solubility: 3 mM in water, 10ľM DMSO
  • Shipping conditions: Dry Ice

Documentation

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References

  • •  VĂŠlez et al. 2017. Open Med Chem J. 11:54-65. PMID: 28761559.
  • •  Otero et al. 2015. J Cancer Res Ther Oncol. 1:. PMID: 26086027.