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Contributor Information

  • Name Osvaldo Cox (Retired), Beatriz Zayas
  • Institute Universidad Ana G. Mendez

Tool Details

  • Tool name: NBQ-95
  • Molecular formula: C16h10Cl2N2O2
  • Tool type: Small molecules
  • Tool sub-type: Inhibitor
  • Molecular weight of the target: 365.24
  • Application: cell hypoxia marker
  • Description: Inhibitor of growth in several cancer cell line models. This small molecule can also be used as a cell hypoxia marker.
  • Research area: Cancer; Fluorescent Cell Imaging
  • IUPAC: 10- methyl-2-chloro-3-nitrobenzothiazolo[3,2-a]quinolinium chloride
  • IC50: 28 uM and 51uM A431 cells

  • For Research Use Only

Target Details

  • Target molecular weight: 365.24

Application Details

  • Application: cell hypoxia marker

Handling

  • Purity: 365.24 g/mol
  • Solubility: 3 mM water
  • Storage conditions: 4°C in solution
  • Shipping conditions: Dry Ice

Documentation

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  • Available on request

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References

  • •  VĂŠlez et al. 2013. Open J Apoptosis. 2(2):13-22. PMID: 25243104.
  • •  Zayas et al. 2007. Toxicol In Vitro. 21(6):1155-64. PMID: 17466486.