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Contributor Information

  • Name Osvaldo Cox (Retired), Beatriz Zayas
  • Institute Universidad Ana G. Mendez

Tool Details

  • Tool name: NBQ-38 small molecule
  • Molecular formula: C17H14ClN3O2
  • Tool type: Small molecules
  • Tool sub-type: Inhibitor
  • Molecular weight of the target: 327.77
  • Application: cell hypoxia marker
  • Description: Inhibitor of growth in several cancer cell line models. This small molecule can also be used as a cell hypoxia marker.
  • Research area: Cancer; Fluorescent Cell Imaging
  • IUPAC: 7-Ethyl-3-nitrobenzimidazolo[3,2-a]quinolinium Chloride
  • IC50: 36-38 uM (A431 cells); 950 uM+/- 26 uM (U937 cells)

  • For Research Use Only

Target Details

  • Target molecular weight: 327.77

Application Details

  • Application: cell hypoxia marker

Handling

  • Purity: 327.77 g/mol
  • Solubility: 100 ľg/mL in DMSO
  • Shipping conditions: Dry Ice

Documentation

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References

  • •  VĂŠlez et al. 2013. Open J Apoptosis. 2(2):13-22. PMID: 25243104.
  • •  Zayas et al. 2007. Toxicol In Vitro. 21(6):1155-64. PMID: 17466486.
  • •  Vivas-MejĂ­a et al. 1998. Mol Cell Biochem. 178(1-2):203-12. PMID: 9546601.