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Contributor Information

  • Name Alessio Ciulli ; Michael Zengerle ; Kwok-Ho Chan
  • Institute University of Dundee

Tool Details

  • Tool name: VH298 small molecule (tool compound)
  • Alternate names: VHL, VHL1, HRCA1, RCA11, pVHL, von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
  • Molecular formula: C27H33N5O4S
  • Tool type: Small molecules
  • Description: High-affinity inhibitor of VHL
  • Research area: Drug Discovery & Development

  • For Research Use Only

Target Details

  • Target: VHL

Application Details

Handling

  • Purity: 523.65 g/mol
  • Solubility: DMSO; Ethanol
  • Shipping conditions: Dry Ice

Documentation

  • Available on request

References

  •   Frost et al. 2016. Nat Commun. 7:13312. PMID: 27811928.