Product Image

Contributor Information

  • Name David Smith ; Zelong Lim ; Elizabeth New
  • Institute University of Sydney

Tool Details

  • Tool name: TcAg1 small molecule (tool compound)
  • Alternate names: Thiocoumarin silver sensor 1
  • Molecular formula: C20N2S2OH18
  • Tool type: Small molecules
  • Tool sub-type: Fluorescent Probe
  • Application: Reversible fluorescent probe for monitoring Ag (I) ions
  • Description: Silver is widely used in industrial applications due to its conductivity and malleability properties, as well as in medicine as an antibiotic coating and in wound treatment. The high toxicity of silver is crucial for the unique antibacterial properties of this metal, but there is concern about the effect of aquatic silver pollution on the fresh water invertebrates and fish. Traditional instrument methods for measuring silver include CIP-MS, GFAAS and voltammetry. However, these techniques require sample preparation or digestion and complex instruments and trained operators, and they lack the ability to differentiate between metallic silver, precipitated silver salts and complexes and free Ag(I). Here an alternative approach has been developed using a fluorescent sensor that can selectively and reversibly respond to Ag(I) ions in solution.
  • Selectivity: Ag(I) ions only
  • IUPAC: 3-(3-Benzoxazolyl)-7-(diethylamino)-2H-1-benzopyran-2-one
  • Additional notes: For application notes please visit PMID:30021927

  • For Research Use Only

Target Details

Application Details

  • Application: Reversible fluorescent probe for monitoring Ag (I) ions




  •   Lim et al. 2018. J R Soc Interface. 15(144):. PMID: 30021927.