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Contributor Information

  • Name Prof Emanuele Buratti
  • Institute International Centre For Genetic Engineering And Biotechnology (ICGEB)

Tool Details

  • Tool name: peQE30-HisNter-TDP1-102 L27A-L28A Vector
  • Alternate names: TARDBP, TAR DNA Binding Protein, TDP-43, TAR DNA-Binding Protein 43, ALS10
  • Tool type: Vector
  • Tool sub-type: pQE30
  • Description: Concentration 1.8mg/ml
  • Research area: Gene Expression; Neurobiology; Virology
  • Bacterial resistance: Ampicillin

  • For Research Use Only

Target Details

  • Target: Mutant TDP43 N-terminal domain 1-102

Application Details

Handling

Documentation

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  • Available on request

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References

  • •  MompeĂĄn et al. 2017. J Biol Chem. 292(28):11992-12006. PMID: 28566288.
  • •  Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions.