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Contributor Information

  • Institute Drexel University

Tool Details

  • Tool name: pM-Gal4-HIF-1a vector
  • Tool type: Vector
  • Tool sub-type: pM
  • Research area: Genetics; Metabolism
  • Bacterial resistance: Ampicillin
  • Selectable markers: Ampicillin, G418

  • For Research Use Only

Target Details

  • Target: HIF-1a (Truncated) and GAL4 (DNA binding domain)

Application Details

Handling

Documentation

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References

  • •  Sang et al. 2003. J Biol Chem. 278(16):14013-9. PMID: 12588875.
  • •  MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300.
  • •  Sang et al. 2002. Mol Cell Biol. 22(9):2984-92. PMID: 11940656.
  • •  Carboxyl-terminal transactivation activity of hypoxia-inducible factor 1 alpha is governed by a von Hippel-Lindau protein-independent, hydroxylation-regulated association with p300/CBP.