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Contributor Information

  • Institute Drexel University

Tool Details

  • Tool name: pTRE/SP N184X w/ 5'UTR vector
  • Tool type: Vector
  • Tool sub-type: pTRE-Tight
  • Research area: Cell biology; Genetics; Neurobiology
  • Bacterial resistance: Ampicillin

  • For Research Use Only

Target Details

  • Target: spastin

Application Details

Handling

Documentation

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References

  • •  Solowska et al. 2017. Mol Biol Cell. 28(13):1728-1737. PMID: 28495799.
  • •  Truncating mutations of SPAST associated with hereditary spastic paraplegia indicate greater accumulation and toxicity of the M1 isoform of spastin.